What special precautions should I follow?
Before taking Sulfasalazine:
Do not take sulfasalazine without first talking to your doctor if you have ever had an allergic reaction to sulfasalazine, a sulfa-based antibiotic, or aspirin; an obstruction (blockage) in your intestines or urinary tract; porphyria; liver disease; kidney disease; asthma; or glucose-6-phosphate dehydrogenase deficiency. You may not be able to take sulfasalazine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Sulfasalazine may decrease the absorption of digoxin (Lanoxin®, Lanoxicaps®). Your doctor may want to monitor the digoxin levels in your blood if you are taking this medicine.
Sulfasalazine may also decrease folate (a natural vitamin) in your body. You may need to take folate supplements or eat folate-rich foods.
Drugs other than those listed here may also interact with sulfasalazine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Sulfasalazine is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take sulfasalazine without first talking to your doctor if you are pregnant.
Moreover, sulfasalazine passes into breast milk and the effects of sulfasalazine on a nursing infant are not known. Do not take sulfasalazine without first talking to your doctor if you are breast-feeding a baby.
The safety and effectiveness of sulfasalazine have not been established for children younger than 2 years of age.
Why is this medication prescribed?
Dosage and using this medicine
What should I do if I forget a dose?
What side effects can this medication cause?