What side effects can this medication cause?
If you experience any of the following serious side effects, stop taking sulfasalazine and seek emergency medical attention or notify your doctor immediately:
an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue, or face, or hives)
worsening colitis (fever, abdominal pain, cramping, or bloody diarrhea)
sore throat
pale skin
bruising
yellow skin or eyes (may indicate a blood disorder)
Other, less serious side effects may be more likely to occur. Continue to take sulfasalazine and talk to your doctor if you experience:
nausea, vomiting, or decreased appetite
headache
a rash, itching, or hives
fever
decreased sperm production (uncommon and usually reversible)
orange-yellow discoloration of the skin or urine (not harmful)
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Why is this medication prescribed?
Dosage and using this medicine
What special precautions should I follow?
What should I do if I forget a dose?